Description: Prokinetic agents are a type of medication that enhances gastrointestinal (GI) motility by increasing the frequency of contractions in the small intestine without disrupting the rhythm. They are often used to treat GI symptoms, such as GERD, bloating, dyspepsia, nausea and vomiting, and constipation. Common mechanism of actions of prokinetics involves the stimulation of the migrating motor complex (MMC) via the bindings of 5-HT (5-hydroxytryptamine) and M (muscarinic) receptors.
